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Mitochondrial DNA mutations in RRF of healthy subjects of different age

✍ Scribed by Antonella Cormio; Francesco Milella; Jacopo Vecchiet; Giorgio Felzani; Maria Nicola Gadaleta; Palmiro Cantatore


Book ID
116780536
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
330 KB
Volume
26
Category
Article
ISSN
0197-4580

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The incidence (frequency of occurrence) and abundance (percentage of mutant out of total mtDNA population) of two different somatic mtDNA mutations in human skin were investigated in 44 subjects ranging from 19 to 87 years of age. Using quantitative allele-specific polymerase chain reaction (AS-PCR)