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Mitochondrial DNA in yeast recombination and subsequent modification following mating between a grande and a suppressive petite

✍ Scribed by Blamire, John ;Michels, Corinne A. ;Walsh, Jean M. ;Friedenberg, Debra L.

Book ID: 104694249
Publisher: Springer
Year: 1976
Tongue: English
Weight: 614 KB
Volume: 143
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00269401

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✦ Synopsis

The fate of mitochondrial DNA, following mating between a grande and suppressive petite of Saccharomyces cerevisiae, has been followed for up to 60 generations. The buoyant density of the mitochondrial DNA was seen to change in a manner explicable by a combination of recombination and subsequent modification phenomena whilst the suppressivity of the petite zygotic clones always remained high. These findings are consistent with current models of mitochondrial DNA metabolism in which petite strains have been observed to undergo deletion and reamplification of certain parts of their genomes.

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