A variety of neurologic phenotypes have been described in patients with mitochondrial disorders. We report a 32-year-old man in whom dystonia was the salient and presenting feature of a mitochondrial DNA mutation. He presented at age 23 with writer's cramp and progressed over 5 years to exhibit dyst
Mitochondrial DNA in focal dystonia: A cybrid analysis
โ Scribed by S. J. Tabrizi; J. M. Cooper; Prof A. H. V. Schapira
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 403 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
โฆ Synopsis
time window for therapeutic measures, such as input manipulation and training, is presently unclear. However, early overuse of a lesion-affected extremity can worsen functional outcome3,* and increase lesion size, possibly due to excessive energy demands causing additional neuronal Further analysis of these interactions is necessary to provide better insights into the implementation of therapeutic strategies in patients with acute focal brain damage.
The investigations were supported by SFB 194 B2.
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