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Mitochondrial DNA in anucleate human blood cells

✍ Scribed by Robert C. Shuster; Andrew J. Rubenstein; Douglas C. Wallace

Book ID
117058707
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
618 KB
Volume
155
Category
Article
ISSN
0006-291X

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The Long PCR followed by the RFLP technique has been used to search for abnormally structured mitochondrial DNA (mtDNA) and specific sequence differences implicated in the pathogenesis of acute lymphoblastic leukaemia (ALL). We have studied 54 specific sites whose combinations define groups of mtDNA