Mitochondrial DNA and genetic disease
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Jo Poulton
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Article
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1992
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John Wiley and Sons
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English
β 770 KB
Since the human mitochondrial genome was characterised and sequenced in 1981(l), it has been viewed as the likely site of genetic diseases showing a maternal inheritance pattern and associated with defects of the respiratory chain, such as the mitochondrial myopathies ( MMS)?(~). The properties that