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Mitochondrial cytochrome c release is caspase-dependent and does not involve mitochondrial permeability transition in didemnin B-induced apoptosis

✍ Scribed by Grubb, David R; Ly, Jennifer D; Vaillant, François; Johnson, Karina L; Lawen, Alfons


Book ID
110064812
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
314 KB
Volume
20
Category
Article
ISSN
0950-9232

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APOPTOSIS INDUCED BY γ IRRADIATION IN PE
✍ H Louagie; P Schotte; A Vral; M Cornelissen; H Thierens; R Beyaert; L De Ridder; 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 212 KB

Caspase 3 has been shown to be actively involved in the apoptotic process in thymocytes after gamma-irradiation. We examined caspase 3 activation in mature peripheral blood lymphocytes (PBL) after gamma irradiation. Since the activation of caspase 3 is generally prceded by a decrease in mitochondria