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Mitochondrial complex I plays an essential role in human respirasome assembly

✍ Scribed by Ugalde, C.; Moreno-Lastres, D.; Fontanesi, F.; García-Consuegra, I.; Martín, M.A.; Barrientos, A.; Arenas, J.


Book ID
121906162
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
51 KB
Volume
1817
Category
Article
ISSN
0005-2728

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## Abstract NADH‐ubiquinone oxidoreductase (complex I) is a large, multimeric enzyme complex involved in the generation of ATP by oxidative phosphorylation. Complex I is comprised of 45 subunits which must be assembled together in a coordinated process to form the mature holoenzyme. In recent years