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Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients

✍ Scribed by Antonio Hernandez-Mijares; Milagros Rocha; Nadezda Apostolova; Consuelo Borras; Ana Jover; Celia Bañuls; Eva Sola; Victor M. Victor

Book ID
113631940
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
613 KB
Volume
50
Category
Article
ISSN
0891-5849

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## Abstract The parkin protein functions as a RING‐type ubiquitin protein ligase. Considering the possibility that impaired ubiquitin‐proteosomal system activity may impair antioxidant defenses and enhance oxidative stress, we have investigated the activity of mitochondrial respiratory enzymes in p