Mitochondrial Calcium Transport and Mitochondrial Dysfunction After Global Brain Ischemia in Rat Hippocampus
β Scribed by Peter Racay; Zuzana Tatarkova; Maria Chomova; Jozef Hatok; Peter Kaplan; Dusan Dobrota
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 356 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0364-3190
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## Abstract Transient global brain ischemia causes delayed neuronal death in the hippocampus that has been associated with impairments in hippocampusβdependent brain function, such as mood, learning, and memory. We investigated the expression of voltageβdependent __Kcnh1__ and __Kcnh5__, __ether Γ
The aim of the present investigation was to evaluate the possible role of arachidonic acid and other free fatty acids in ischemia-induced mitochondrial dysfunction. Respiratory activities were measured in mitochondria isolated from rat brains subjected to 15-30 min of decapitation ischemia. Addition