Mitochondrial alterations associated with avian reticuloendotheliosis virus (strain T) pathogenicity

Hepatitis C virus JFH-1 strain infection

Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation

✍ Takanobu Kato; Youkyung Choi; Gamal Elmowalid; Ronda K. Sapp; Heidi Barth; Akihi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 481 KB 👁 1 views

The identification of the hepatitis C virus (HCV) strain JFH-1 enabled the successful development of infectious cell culture systems. Although this strain replicates efficiently and produces infectious virus in cell culture, the replication capacity and pathogenesis in vivo are still undefined. To a