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Mitochondrial activity is required for the expression ofIME1, a regulator of meiosis in yeast

✍ Scribed by Millet Treinin; Giora Simchen


Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
671 KB
Volume
23
Category
Article
ISSN
0172-8083

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✦ Synopsis


Sporulation in the yeast Saccharomyces cerevisiae occurs in diploid cells following starvation for glucose and nitrogen sources. A key gene in the regulation of the meiotic process is IME1. A well-documented fact is that respiration is necessary for sporulation. We now show that respiration is necessary for the expression of IME1. We suggest that glucose repression of meiosis is transduced through its effect on respiration, in a pathway separate from that of adenylyl cyclase.


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