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Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic β-cells

✍ Scribed by Maechler, Pierre; Kennedy, Eleanor D.; Pozzan, Tullio; Wollheim, Claes B.

Book ID
111744860
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
522 KB
Volume
16
Category
Article
ISSN
0261-4189

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This study was designed in order to examine the expression and functional role of syntaxin 2/epimorphin in pancreatic b cells. Northern blot analysis revealed that syntaxin 2 mRNA was able to be detected in mouse bTC3 cells, but not in isolated mouse islets. In agreement with this result, immunoblot