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Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications

โœ Scribed by Parvesh Bubber; Vahram Haroutunian; Gene Fisch; John P. Blass; Gary E. Gibson


Book ID
101467487
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
244 KB
Volume
57
Category
Article
ISSN
0364-5134

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The most striking feature of Alzheimer's disease (AD) is the number of abnormalities affecting essentially every aspect of brain homeostasis. Recent work suggests that increased oxidative stress that damages lipids, proteins, and nucleic acids and results in the accumulation of redox-active metals m