Mitochondria Mediate Nitric Oxide-Induced Cell Death
β Scribed by ANNA BAL-PRICE; VILMA BORUTAITE; GUY C. BROWN
- Book ID
- 111395149
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 144 KB
- Volume
- 893
- Category
- Article
- ISSN
- 0890-6564
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π SIMILAR VOLUMES
Neuronal injury is intricately linked to the activation of three distinct neuronal endonucleases. Since these endonucleases are exquisitely pH dependent, we investigated in primary rat hippocampal neurons the role of intracellular pH (pH i ) regulation during nitric oxide (NO)-induced toxicity. Neur
## Abstract It is commonly accepted that the major effect of nitroglycerin (NG) is realized through the release of nitric oxide (NO) catalyzed by aldehyde dehydrogenaseβ2 (ALDH2). In addition, it has been shown that NG inhibits mitochondrial respiration. The aim of this study was to clarify whether