## Abstract Astrocytes, the most abundant glial cell population in the central nervous system (CNS), play physiological roles in neuronal activities. Oxidative insult induced by the injury to the CNS causes neural cell death through extrinsic and intrinsic pathways. This study reports that reactive
β¦ LIBER β¦
Mitochondria-derived Reactive Oxygen Species Mediate Blue Light-induced Death of Retinal Pigment Epithelial Cells
β Scribed by Ayala King; Eyal Gottlieb; David G. Brooks; Michael P. Murphy; Joshua L. Dunaief
- Book ID
- 111412739
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 687 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0031-8655
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## Abstract __N__β(4βhydroxyphenyl)retinamide (4HPR, fenretinide), a retinoic acid (RA) derivative and a potential cancer preventive agent, is known to exert its chemotherapeutic effects in cancer cells through induction of apoptosis. Earlier work from our laboratory has shown that relatively low c