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Mitochondria and Neurodegeneration

✍ Scribed by Lucia Petrozzi; Giulia Ricci; Noemi J. Giglioli; Gabriele Siciliano; Michelangelo Mancuso

Book ID: 106372634
Publisher: Springer
Year: 2007
Tongue: English
Weight: 235 KB
Volume: 27
Category: Article
ISSN: 0144-8463
DOI: 10.1007/s10540-007-9038-z

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## Abstract A critical role of mitochondrial dysfunction and oxidative damage has been hypothesized in both aging and neurodegenerative diseases. Much of the evidence has been correlative, but recent evidence has shown that the accumulation of mitochondrial DNA mutations accelerates normal aging, l