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Mitochondria and cell death: outer membrane permeabilization and beyond

✍ Scribed by Tait, Stephen W. G.; Green, Douglas R.

Book ID
109959416
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
674 KB
Volume
11
Category
Article
ISSN
1471-0072

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Mitochondria are essential for maintaining cell life but they also play a role in regulating cell death, which occurs when their membranes become permeabilized. Mitochondria possess two distinct membrane systems including an outer membrane in close communication with the cytosol and an inner membran