## Abstract Methylene blue (MB), a widely studied reagent, is investigated in this work for its usage in photodynamic therapy (PDT). PDT has been proved to be highly effective in the treatment of different types of cancers. Previous studies showed MB has both high affinity for mitochondria and high
Mitochondria and calpains mediate caspase-dependent apoptosis induced by doxycycline in HeLa cells
✍ Scribed by J. Wu; T. Liu; J. Xie; F. Xin; L. Guo
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 466 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Cisplatin, an effective anticancer agent, can induce tumor cell apoptosis via caspase‐dependent and‐independent pathways. However, the precise mechanism that regulates the pathways remains unclear. In this study, we showed that μ‐calpain mediated both caspase‐dependent and‐independent p
## Abstract Cadmium, a well‐known environmental hazard, has caused serious health problems in humans and animals. Accumulating evidence suggests the cadmium toxicity is mediated by oxidative stress‐induced cell death. However, the molecular signaling underlying cadmium‐induced apoptosis remains unc
## Abstract The mitochondria‐mediated apoptotic pathway is regulated by members of the Bcl‐2 family. Epidermal growth factor (EGF) induces Bad phosphorylation at Ser~112~ via mitogen‐activated protein kinase (MAPK), impairing its binding to Bcl‐2 and Bcl‐xL and interfering with their anti‐apoptotic