## Abstract Amyloid formation plays a central role in the cause and progression of Alzheimer's disease. The major component of this amyloid is the amyloid‐β (Aβ) peptide, which is currently the subject of intense study. This review discusses some recent studies in the area of Aβ synthesis, purifica
Mitochondria and Alzheimer’s disease: amyloid-β peptide uptake and degradation by the presequence protease, hPreP
✍ Scribed by Nyosha Alikhani; Maria Ankarcrona; Elzbieta Glaser
- Publisher
- Springer US
- Year
- 2009
- Tongue
- English
- Weight
- 171 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0145-479X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Aggregated amyloid β‐peptide (Aβ) is the primary constituent of the extracellular plaques and perivascular amyloid deposits associated with Alzheimer's disease (AD). Deposition of the cerebral amyloid plaques is thought to be central to the disease progression. One such molecule that ha
## Abstract The neuropathological features associated with Alzheimer's disease (AD) brain include the presence of extracellular neuritic plaques composed of amyloid β protein (Aβ), intracellular neurofibrillary tangles containing hyperphosphorylated tau protein, and the loss of basal forebrain chol