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Mitissimolone, a New Sesquiterpene with a Novel Carbon Skeleton from the Basidiomycete Lactarius mitissimus

โœ Scribed by Du-Qiang Luo; Shu-Juan Liang; Yao-Long Shi; Hong-Liang Tang


Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
160 KB
Volume
92
Category
Article
ISSN
0018-019X

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โœฆ Synopsis


Abstract

Mitissimolone, a new regular sesquiterpene possessing a novel carbon skeleton, was isolated from the EtOH extract of fruiting bodies of Lactarius mitissimus. Its structure was determined by extensive spectroscopic analyses including 1Dโ€ and 2Dโ€NMR spectra. Mitissimolone inhibited moderately the growth of HeLa cells lines, with an IC~50~ value of 29.8โ€…ฮผg/ml.


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