Mistranslation of Membrane Proteins and
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Michael A. Kohanski; Daniel J. Dwyer; Jamey Wierzbowski; Guillaume Cottarel; Jam
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Article
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2008
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Elsevier Science
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English
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Aminoglycoside antibiotics, such as gentamicin and kanamycin, directly target the ribosome, yet the mechanisms by which these bactericidal drugs induce cell death are not fully understood. Recently, oxidative stress has been implicated as one of the mechanisms whereby bactericidal antibiotics kill b