Missing genes in metabolic pathways: a comparative genomics approach

✍ Scribed by Andrei Osterman; Ross Overbeek

• Book ID: 104414757
• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 222 KB
• Volume: 7
• Category: Article
• ISSN: 1367-5931
• DOI: 10.1016/s1367-5931(03)00027-9

✦ Synopsis

The new techniques of genome context analysis--chromosomal gene clustering, protein fusions, occurrence profiles and shared regulatory sites--infer functional coupling between genes. In combination with metabolic reconstructions, these techniques can dramatically accelerate the pace of gene discovery.