๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Missense meanderings in sequence space: a biophysical view of protein evolution

โœ Scribed by DePristo, Mark A.; Weinreich, Daniel M.; Hartl, Daniel L.


Book ID
109952169
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
350 KB
Volume
6
Category
Article
ISSN
1471-0056

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Neutral Evolution of Model Proteins: Dif
โœ Ugo Bastolla; H.Eduardo Roman; Michele Vendruscolo ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 244 KB

We stimulate the evolution of model protein sequences subject to mutations. A mutation is considered neutral if it conserves (1) the structure of the ground state, (2) its thermodynamic stability and (3) its kinetic accessibility. All other mutations are considered lethal and are rejected. We adopt