MLH1 โ93G>A promoter polymorphism and ri
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James M. Allan; Jennifer Shorto; Julian Adlard; Jonathan Bury; Ron Coggins; Rina
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Article
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2008
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John Wiley and Sons
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French
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## Abstract Rare inherited mutations in the __mutL homolog 1__ (__MLH1__) DNA mismatch repair gene can confer an increased susceptibility to colorectal cancer (CRC) with high penetrance where disease frequently develops in the proximal colon. The core promoter of __MLH1__ contains a common single n