## Abstract A clonal derivative named P19CL6 has been isolated from pluripotent P19 mouse embryonic carcinoma cells, and this subline efficiently differentiates into beating cardiomyocytes when treated with 1% dimethyl sulfoxide (DMSO). It offers a valuable model to study cardiomyocytes differentia
Misexpression of mouse porcupine isoforms modulates the differentiation of P19 embryonic carcinoma cells
โ Scribed by Kimiko Tanaka; Yasuo Kitagawa; Tatsuhiko Kadowaki
- Book ID
- 108485569
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 761 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1065-6995
No coin nor oath required. For personal study only.
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During embryonic development, cells not only increase in number, they also undergo specialization and differentiate into diverse cell types that are organized into different tissues and organs. Nervous system development, for example, involves a complex series of events such as neuronal and astrogli
## Background Pluripotent cells maintain a unique gene expression pattern and specific chromatin signature. In this study, we explored the effect of the methyltransferase inhibitor adenosine dialdehyde (AdOx) on pluripotency maintenance and gene expression in P19 embryonal carcinoma cells. ## Resu