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Mise en évidence de groupements actifs dans les alkylpyrimidines. Étude de la mobilité des Hydrogènes par échange isotopique hydrogène-deutérium. I. - Étude cinétique qualitative

✍ Scribed by Pierre Dizabo; Jean-Claude Monier; Alain Pompon


Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
415 KB
Volume
7
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

Methyl groups bound to heterocyclic rings may, in certain circumstances, exchange hydrogen for deuterium. This exchange has been studied for alkyl or amino‐alkylpyrimidines in acid medium. The qualitative results obtained as a function of acidity, substituant location and temperature confirm the reaction mechanism proposed by Brown except in the case of amino‐2 dimethyl‐4, 6 pyrimidine.