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Mirtazapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation

โœ Scribed by Kazuhiko Nakayama; Takashi Sakurai; Hisatoshi Katsu


Book ID
116325979
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
91 KB
Volume
63
Category
Article
ISSN
0361-9230

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Serotonin, (5-HT3) receptors are found in high density in the mesocorticolimbic dopamine (DA) system (Kilpatrick et al., 1987). It has been suggested that 5-HT3 antagonists inhibit mesolimbic portions of this DA system involved in brain-stimulation reward and drug-induced reward, and that this inhib