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miR-210 as a marker of chronic hypoxia, but not a therapeutic target in prostate cancer

โœ Scribed by Laurent Quero; Ludwig Dubois; Natasja G. Lieuwes; Christophe Hennequin; Philippe Lambin


Book ID
118497999
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
521 KB
Volume
101
Category
Article
ISSN
0167-8140

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## Abstract ## BACKGROUND: Hypoxia is an important mechanism of treatment resistance in head and neck squamous cell carcinoma (HNSCC). MicroRNAs are short noncoding RNAs that regulate multiple mRNAs and are frequently dysregulated in cancer. The authors have investigated the role of 3 microRNAs, i