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MiR -206 Regulates Neural Cells Proliferation and Apoptosis via Otx2

โœ Scribed by Wang, Rui; Hu, Yi; Song, Ge; Hao, Chan Juan; Cui, Yi; Xia, Hong-Fei; Ma, Xu


Book ID
120612055
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
767 KB
Volume
29
Category
Article
ISSN
1015-8987

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## Abstract JMJD2A is a transcriptional cofactor and enzyme that catalyzes demethylation of histone H3 lysines 9 and 36 and is overexpressed in human tumors, but its role in oncogenesis remains unclear. Here, we show that JMJD2A interacts with the tumor suppressor p53 both in vitro and in HCT116 co