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miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A

✍ Scribed by Xufu Wei; Tingxiu Xiang; Guosheng Ren; Cui Tan; Rui Liu; Xiao Xu; Zhongjun Wu


Book ID
117989864
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
497 KB
Volume
25
Category
Article
ISSN
0898-6568

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The hepatitis B virus (HBV) X protein has been implicated as a potential trigger of the epigenetic modifications of some genes during hepatocarcinogenesis, but the underlying mechanisms remain unknown. MicroRNAs (miRNAs), which are noncoding RNAs that regulate gene expression, are involved in divers