𝔖 Bobbio Scriptorium
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Minute virus of mice inhibits cell transformation by simian virus 40

✍ Scribed by Mousset, S.; Rommelaere, J.

Book ID
109729323
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
394 KB
Volume
300
Category
Article
ISSN
0028-0836

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## Abstract Mammalian cells transformed in tissue culture by SV40 were shown to contain, in addition to the SV40‐coded 94,000 d large T antigen and the 20, 000 d small t antigen, a ∼ 56,000 d cellular protein, which specifically precipitates with sera of animals bearing SV40‐induced tumor (s) (tumo

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## Abstract Although BHK 21 cells remain refractory to direct transformation by SV40 virus even at multiplicities of infection as high as 10^4^ PFU per cell, transformed derivatives may be produced by cocultivation of the untransformed cells with monkey cells infected with SV40 virus. The characte