𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Minor depression and brain perfusion images in Parkinson's disease

✍ Scribed by Hideaki Matsui; Kazuto Nishinaka; Masaya Oda; Kenichi Komatsu; Tamotsu Kubori; Fukashi Udaka

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
129 KB
Volume
21
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Depression is common in individuals with Parkinson's disease. However, the pathophysiology of depression in Parkinson's disease remains obscure. Here we compared brain perfusion images of Parkinson's disease patients with and without depression to investigate correlations between depression and brain perfusion images in Parkinson's disease. We divided 40 consecutive patients with Parkinson's disease into two groups: patients with minor depression (n ϭ 22) and patients without depression (n ϭ 18). We then compared brain perfusion images between the two groups. As a result, hypo-perfusion of the left superior and inferior frontal gyrus was demonstrated in depressed patients. These results were partially in agreement with previous studies on de novo and parkinsonian major depression. We could not conclude on whether pathophysiological mechanisms differed between de novo depression and depression with Parkinson's disease, and between major and minor depressions.

📜 SIMILAR VOLUMES

Three-dimensional stereotactic surface p
Three-dimensional stereotactic surface projection study of freezing of gait and brain perfusion image in Parkinson's disease
✍ Hideaki Matsui; Fukashi Udaka; Takafumi Miyoshi; Narihiro Hara; Akiko Tamaura; M 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB

## Abstract Gait disturbance is a cardinal symptom in patients with Parkinson's disease. Among the gait disturbances, freezing of gait is a unique and troublesome symptom, but its mechanism is unclear. We compared brain perfusion images using three‐dimensional stereotactic surface projection analys

Amnestic mild cognitive impairment in Pa
Amnestic mild cognitive impairment in Parkinson's disease: A brain perfusion SPECT study
✍ Flavio Nobili; Giovanni Abbruzzese; Silvia Morbelli; Roberta Marchese; Nicola Gi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract The purpose of this study was to investigate cortical dysfunction in Parkinson's disease (PD) patients with amnestic deficit (PD‐MCI). Perfusion single photon emission computed tomography was performed in 15 PD‐MCI patients and compared (statistical parametric mapping [SPM2]) with three

Bereitschaftspotential in depressed and
Bereitschaftspotential in depressed and non-depressed patients with Parkinson's disease
✍ Saša R. Filipović; Nadežda Šternić; Marina Svetel; Nataša Dragašević; Dušica Leč 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB

## Abstract Impaired initiation and slowed execution of movements are two of the principal characteristics of Parkinson's disease (PD). A similar pattern of movement impairments (psychomotor retardation) can be seen frequently in patients with idiopathic depression. In addition, affective disorders

Depression and major depressive disorder
Depression and major depressive disorder in patients with Parkinson's disease
✍ Takeshi Inoue; Mayumi Kitagawa; Teruaki Tanaka; Shin Nakagawa; Tsukasa Koyama 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

## Abstract The prevalence of depression in Parkinson's disease (PD) varies greatly. In this study, we investigated major depressive disorder (MDD) and depressive symptoms without MDD in patients with PD. The psychopathological characteristics of depressive symptoms were assessed by a psychiatric i

Subthreshold depression in Parkinson's d
Subthreshold depression in Parkinson's disease
✍ Daniel A. Nation; Heather L. Katzen; Spyridon Papapetropoulos; Blake K. Scanlon; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB 👁 2 views

## Abstract ## Objective It is estimated that 40% of patients with Parkinson's disease (PD) are clinically depressed, however, little is known about the frequency and associated features of subthreshold depression in PD. The current study sought to determine the prevalence of subthreshold depressi