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Minocycline-induced hyperpigmentation: Treatment with the Q-switched Nd:YAG Laser

✍ Scribed by Greve, Baerbel; Schönermark, Matthias P.; Raulin, Christian

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
238 KB
Volume
22
Category
Article
ISSN
0196-8092

No coin nor oath required. For personal study only.

✦ Synopsis

Background and objective:

Cutaneous hyperpigmentations are well-documented, but nevertheless rare side-effects of high-dose or long-term minocycline therapy. the pigmental changes, may last for years, even though therapy has been abrogated. to date, no safe and effective therapy has been described to target this cosmetically disturbing sequela.

Study design/materials and methods:

A 57-year-old female patient with extensive pigmental changes of the face due to long-term minocycline therapy was treated in eight consecutive sessions with the q-switched nd:yag-laser (1,064-nm wavelength, 5- to 7-nsec impulse length).

Results:

A 90% resolution of the pigmentation could be achieved after five treatments. after the last session the lesions were completely gone; no hypopigmentation scars, or other side-effects were observed.

Conclusion:

Treatment with the q-switched nd:yag laser seems to be an effective, safe, and easily applicable strategy for the therapy of minocycline-induced hyperpigmentations.

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