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Minnelide induces cell death in pancreatic cancer through regulation of the transcription factor Sp1

✍ Scribed by Banerjee, Sulagna; Sangwan, Veena; McGinn, Olivia; Dudeja, Vikas; Chugh, Rohit; Vickers, Selwyn; Saluja, Ashok

Book ID
122807711
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
45 KB
Volume
13
Category
Article
ISSN
1424-3903

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Sp1 and krΓΌppel-like factor family of tr
Sp1 and krΓΌppel-like factor family of transcription factors in cell growth regulation and cancer
✍ Adrian R. Black; Jennifer D. Black; Jane Azizkhan-Clifford πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 232 KB

## Abstract The Sp/KLF family contains at least twenty identified members which include Sp1‐4 and numerous krΓΌppel‐like factors. Members of the family bind with varying affinities to sequences designated as β€˜Sp1 sites’ (e.g., GC‐boxes, CACCC‐boxes, and basic transcription elements). Family members