Activation of the Nrf2βARE signaling pat
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Aldo Giudice; Maurizio Montella
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Article
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2006
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John Wiley and Sons
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English
β 193 KB
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A major protective mechanism against oxidizing substances capable of damaging DNA integrity and initiating carcinogenesis is the induction of phase II detoxification and antioxidant enzymes by chemopreventive agents. A key finding in the field of chemoprevention has been the discovery that the induc