Minimizing contrast agent dose during intraarterial gadolinium-enhanced MR angiography: In vitro assessment
✍ Scribed by Ken-Pin Hwang; Jordin D. Green; Debiao Li; Orlando P. Simonetti; Scott A. Resnick; J. Paul Finn; Jeffrey L. Duerk; Reed A. Omary
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 540 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To minimize contrast agent dosage for intra‐arterial (IA) contrast‐enhanced magnetic resonance angiography (CE‐MRA) by examining the effects of encoding order (elliptical vs. sequential) and injection duration (100% to 30% of the acquisition time).
Materials and Methods
Catheter‐based IA gadolinium (Gd) injections were performed in an arterial flow phantom. Blood flow rates, injection rates, and injection durations were systematically varied. Signal‐to‐noise (SNR) measurements were obtained in the aorta, renal artery, and common iliac artery.
Results
No significant SNR losses were observed for any of the vessels with 75% injection duration, or for the aorta and iliac artery with 50% injection duration. Excellent images of all vessels were obtained at 50% injection duration. There was no significant SNR difference between encoding schemes.
Conclusion
Contrast agent dosage can be substantially reduced without loss of SNR by limiting injection to part of the imaging acquisition time. J. Magn. Reson. Imaging 2002;15:55–61. © 2002 Wiley‐Liss, Inc.