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Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks

โœ Scribed by S. Schuster; R. Heinrich


Publisher
Springer
Year
1991
Tongue
English
Weight
934 KB
Volume
29
Category
Article
ISSN
0303-6812

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Minimization of intermediate concentrati
โœ S. Schuster; R. Schuster; R. Heinrich ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 688 KB

The multiobjective problem of minimizing all intermediate concentrations is solved for a model of glycolysis, the pentose monophosphate shunt and the glutathione system in human erythrocytes. It turns out that one solution out of four obtained corresponds qualitatively to the real system. Furthermor