Minimally ablative resurfacing with the confluent 2,790 nm erbium:YSGG Laser: A pilot study on safety and efficacy
✍ Scribed by Susan E. Walgrave; David A. Kist; Ayse Noyaner-Turley; Brian D. Zelickson
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 325 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background
The 2,790 nm Er:YSGG wavelength has a lower water absorption coefficient than the 2,940 nm Er:YAG, but a higher coefficient than the 10,600 nm CO~2~ laser. This allows ablative resurfacing with mild thermal coagulation, which may increase clinical efficacy while reducing patient downtime.
Objectives
To evaluate the efficacy and safety of the confluent 2,790 nm Erbium:YSGG (Pearl™, Cutera) laser for facial rejuvenation.
Study Design/Materials and Methods
Eleven subjects (mean age 50, skin types I–III) with mild to moderate photodamage and wrinkles had two facial treatments with the 2,790 nm Er:YSGG laser using a fluence of 3.5 J/cm^2^, pulse duration of 0.4 msecond, and 20% overlap. Treatments were performed 6 weeks apart. Pre‐auricular biopsies from five subjects were evaluated at baseline and 6 weeks after the final treatment. Data from blinded photo assessments and subjects' self‐assessment of improvement were analyzed 6 weeks after the final treatment. Additionally, long‐term safety and efficacy were evaluated 2 years after the final treatment.
Results
Histologically, 80% of subjects had new collagen formation in the dermal grenz zone, and 60% had increased epidermal thickness. Almost all subjects (91%) showed improvement in tone/texture, 82% of subjects showed improvement in dyschromia and fine lines, and 54% showed improvement in wrinkles 6 weeks after the final treatment. Subjects' self assessment indicated “significant” to “dramatic” improvement in dyschromia (91% of subjects) and tone/texture (82%) 6 weeks after the final treatment. All subjects saw “mild” to “significant” improvement in fine lines and wrinkles. At the 2‐year follow‐up visit, 57% of the overall improvement achieved at 6 weeks was maintained. No adverse events were reported throughout the study.
Conclusion
Ablative resurfacing with the 2,790 nm Er:YSGG laser demonstrated visible improvement in photodamage with good tolerability and minimal downtime. Subjects were highly satisfied, especially with respect to dyschromia, skin tone, and texture. Lasers Surg. Med. 44:103–111, 2012. © 2012 Wiley Periodicals, Inc.