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Minimal residual disease after intensive induction therapy in childhood acute lymphoblastic leukemia predicts outcome

✍ Scribed by Gruhn, B; Hongeng, S; Yi, H; Hancock, M L; Rubnitz, J E; Neale, G A M; Kitchingman, G R


Book ID
110053813
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
102 KB
Volume
12
Category
Article
ISSN
0887-6924

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## Abstract In vivo response to initial therapy, as assessed by determination of minimal residual disease (MRD) after 5 and 12 weeks of treatment, has evolved as a strong prognostic factor in children with acute lymphoblastic leukemia (ALL) treated according to the BFM regime. Individual treatment