A new approach to minimizing the number
β
E. SchΓΌtz; H. Fuchs
π
Article
π
1982
π
Springer-Verlag
π
English
β 788 KB
170 acute toxicity determinations, carried out in rats, mice, and guinea pigs after oral and parenteral administration during the past 5 years, using 5 c~/5 9 animals per dose, were evaluated with respect to the possibility of a reduction of animals necessary for obtaining LDs0 values with limits of