Miniemulsion Polymerizations Using Static Mixers: Towards High Biocompatible Hydrophobe Contents

✍ Scribed by Roland Rahme; Christian Graillat; Gholamali Farzi; Timothy F. L. McKenna; Thierry Hamaide

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 300 KB
• Volume: 211
• Category: Article
• ISSN: 1022-1352
• DOI: 10.1002/macp.201000302

✦ Synopsis

Abstract

Simple static mixers have been used as homogenization devices to perform polymerizable miniemulsion dispersions with negligible heat generation from mixtures containing vinyl acetate as the monomer and high amounts of biocompatible viscous oils (Miglyol and vitamin E acetate) as the hydrophobic components. A triblock non‐ionic copolymer was used as surfactant. The size of the initial droplets was in the 100–300 nm range, increasing with the amount of the hydrophobe oil. These droplets have successfully been polymerized by using lauroyl peroxide or H~2~O~2~/ascorbic acid as initiators in order to get non‐charged primary radicals. Stable nanoparticles with sizes around 300 nm have been obtained that display colloidal stabilization at 4 and 25 °C upon a long storage time. magnified image