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Mineralocorticoid receptor antagonists attenuate pulmonary inflammation and bleomycin-evoked fibrosis in rodent models

✍ Scribed by Lieber, Gissela B; Fernandez, Xiomara; Mingo, Garfield G; Jia, Yanlin; Caniga, Michael; Gil, Malgorzata A.; Keshwani, Shanil; Woodhouse, Janice D.; Cicmil, Milenko; Moy, Lily Y; Kelly, Nancy; Jimenez, Johanna; Crawley, Yvette; Anthes, John C; Klappenbach, Joel; Ma, Yu-Lu; McLeod, Robbie L.

Book ID
122004589
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
702 KB
Volume
718
Category
Article
ISSN
0014-2999

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## Abstract ## Purpose: To investigate the ability of proton (^1^H) magnetic resonance imaging (MRI) to distinguish between pulmonary inflammation and fibrosis. ## Materials and Methods: Three groups of Sprague‐Dawley rats (n = 5) were instilled intratracheally with bleomycin (2.5 U/kg or 3.5 U/