✦ LIBER ✦

Mineral fiber concentration in lung tissue of mesothelioma patients in finland

✍ Scribed by Timo Tuomi; Margaretha Segerberg-Konttinen; Lauri Tammilehto; Antti Tossavainen; Esa Vanhala

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 460 KB
Volume: 16
Category: Article
ISSN: 0271-3586
DOI: 10.1002/ajim.4700160303

No coin nor oath required. For personal study only.

✦ Synopsis

The mineral fibers in lung tissue samples of 19 mesothelioma patients and 15 randomly selected autopsy cases were analyzed using low-temperature ashing, scanning electron microscopy (SEM) and x-ray microanalysis. The fiber concentration ranged from 0.5 to 370 million fibers per gram of dry tissue in the mesothelioma group and from < 0.1 to 3.2 million fibers per gram of dry tissue in the autopsy group. In 80% of the mesothelioma patients and in 20% of the autopsy cases, the fiber concentration exceeded I million fibers per gram of dry tissue. Amphibole asbestos fibers predominated in both groups, and only a few chrysotile fibers were found. In the lungs of six mesothelioma patients, anthophyllite was the main fiber type. The overall analytical precision of sample preparation and fiber counting with SEM was 22%.

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