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Milling-induced disorder of pharmaceuticals: One-phase or two-phase system?

✍ Scribed by Brian S. Luisi; Ales Medek; Zhouyuan Liu; Praveen Mudunuri; Brian Moulton

Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
628 KB
Volume
101
Category
Article
ISSN
0022-3549

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## Abstract **BACKGROUND:** R‐mandelic acid is an important chiral pharmaceutical intermediate, which is commonly obtained by biotransformation. This work has focused on using novel chiral recognition technology, aqueous two‐phase extraction, for the chiral separation of mandelic acid. **RESULTS:*