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Miller fisher syndrome presents as an acute voice change to hypernasal speech

✍ Scribed by Rebecca J. Howell; Alexandra G. Davolos; Matthew S. Clary; Paul C. Frake; Arjun S. Joshi; Houtan Chaboki


Book ID
102452086
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
59 KB
Volume
120
Category
Article
ISSN
0023-852X

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✦ Synopsis


Abstract

The authors describe a 38‐year‐old man who presented with hypernasality, perioral and acroparesthesia, dyspnea, and dysphagia. Further evaluation revealed a diagnosis of Miller‐Fisher syndrome (MFS). MFS is a variant of Guillain‐Barré syndrome previously described in neurology and critical care journals; however, there is a paucity of work concerning this disease in the otolaryngology literature. An acute change in voice usually occurs secondary to inflammatory processes as seen after intubation and infection, but can occur as part of a more complex disease entity such as Guillain‐Barré or Miller‐Fisher syndrome. As such, clinicians should consider this in their evaluation of rhinolalia aperta. Laryngoscope, 2010