✦ LIBER ✦

Milestones in neuroimaging

✍ Scribed by A. Jon Stoessl; David J. Brooks; David Eidelberg

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 291 KB
Volume: 26
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.23679

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✦ Synopsis

Abstract

In the last 25 years there have been enormous advances in brain imaging. In addition to utility in diagnosis, these have led to novel insights into the pathogenesis of basal ganglia disease and the role of dopamine and the basal ganglia in normal health. The authors review highlights of this work, with a focus on advances in Parkinson's disease, the dystonias, Huntington's disease, and the role of dopamine in cognition and reward signaling. Emerging areas for future development include studies of functional connectivity, the analysis of default mode networks, studies of novel neurochemical pathways, methods to study disease pathogenesis, and the application of imaging techniques to investigate animal models of disease. © 2011 Movement Disorder Society

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