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✦ LIBER ✦
Mild oxidative cyclization of sydnone-benzoylhydrazone with lead oxide to 2,5-disubstituted-1,3,4-oxadiazole–sydnone hybrid derivatives
✍ Scribed by Kuo-Chen Chiang; Fung Fuh Wong; Chih-Hao Hung; Yu-Ying Huang; Po-Wei Chang; Liao Yang-Ming; Lin Shao-Kai
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2009
- Tongue
- English
- Weight
- 89 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.21
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✦ Synopsis
Abstract
magnified image
The mild oxidation of sydnone‐benzoylhydrazone hybrids with lead oxide in acetic acid/dichloromethane solution inducted their intramolecular cyclization to provide the corresponding 2,5‐disubstituted‐1,3,4‐oxidiazole derivatives. The sydnone moiety has been efficient preserved for the future work in the mild oxidation. J. Heterocyclic Chem., (2009).
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