A one-pot preparation of carboxylic acids is described that proceeds from their corresponding amides by a 'dry' hydrolysis with phthalic anhydride in the absence of water and solvent. The method affords carboxylic acids in good yields and is applicable to a variety of substrates.
β¦ LIBER β¦
Mild nitrosation and hydrolysis of polyfunctional amides
β Scribed by David A. Evans; Percy H. Carter; Christopher J. Dinsmore; James C. Barrow; Jeffrey L. Katz; Daniel W. Kung
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 277 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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