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Mild Method for the Selective Esterification of Carboxylic Acids Based on the Garegg−Samuelsson Reaction

✍ Scribed by Morcillo, Sara P.; Álvarez de Cienfuegos, Luis; Mota, Antonio J.; Justicia, José; Robles, Rafael


Book ID
111683493
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
915 KB
Volume
76
Category
Article
ISSN
0022-3263

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The Lewis-acid mediated transfer of an alkoxide ligand from the chiral ligand sphere of Ti-TADDOLates ! to cyclic carboxylic acid derivatives is described. The kinetic resolution of dioxolanones, azlactones and biaryl lactones by the Ti-TADDOLates affords, after recrystallization, ester products in