Mild and regioselective oxidative bromination of anilines using potassium bromide and sodium perborate

✍ Scribed by Didier Roche; Kapa Prasad; Oljan Repic; Thomas J Blacklock

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 110 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00119-2

✦ Synopsis

The selective monobromination of various deactivated anilines using potassium bromide and sodium perborate as oxidant has been achieved. The use of ammonium molybdate as catalyst accelerates the rate of reaction but is not essential to obtain good yields and high selectivities.